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Output File Formats

There are several classes of output from Multi-Dendrix. This page will explain each of the files, and give an overview of the file formats.

Collections of gene sets

The collections of pathways identified by Multi-Dendrix are stored as individual, tab-separated text files. The files represent tables in the following format:

Weight Direct interactions statistic (optional) Direct interactions P-value (optional) Genes
61 2 0.0 CDKN2B, CDK4, RB1
57 1 0.0 CDKN2A, TP53, DTX3

Subtype analysis

The analysis of subtype-specific mutations is output in a tab-separated table of the following format:

Gene (Sub)-type Type Mutations Type Normal Non-Type Mutations Non-Type Normal P-Value Bonferonni- Corrected P-Value
TP53 Basal-like 74 24 112 313 2.55E-19 1.53E-18

Permuted data

Mutation matrix

Output from the permute_mutation_data module. Same output format as the input mutation data format (see Input File Formats).

PPI networks

Output from the permute_ppi_network module. Same output format as the input PPI network format (see Input File Formats).